Houston Astros at Chicago Cubs
First pitch: Friday, May 22, 2026 1:20 PM CDT
Venue: Wrigley Field
Houston Astros SP: Spencer Arrighetti (5-1, ERA 1.50)
Chicago Cubs SP: Jameson Taillon (2-3, ERA 4.97)

Houston Astros lineup:
1. Jeremy Peña - SS (.259, OPS .638)
2. Isaac Paredes - 3B (.244, OPS .711)
3. Yordan Alvarez - DH (.303, OPS 1.017)
4. Christian Walker - 1B (.255, OPS .819)
5. Jake Meyers - CF (.227, OPS .641)
6. Braden Shewmake - 2B (.291, OPS .782)
7. Cam Smith - RF (.206, OPS .618)
8. Zach Cole - LF (.186, OPS .624)
9. Christian Vázquez - C (.247, OPS .709)

Chicago Cubs lineup:
1. Nico Hoerner - 2B (.264, OPS .739)
2. Michael Busch - 1B (.233, OPS .735)
3. Alex Bregman - 3B (.249, OPS .682)
4. Ian Happ - LF (.215, OPS .782)
5. Seiya Suzuki - RF (.269, OPS .824)
6. Michael Conforto - DH (.322, OPS 1.041)
7. Carson Kelly - C (.297, OPS .779)
8. Pete Crow-Armstrong - CF (.225, OPS .659)
9. Dansby Swanson - SS (.191, OPS .653)